WATCH: Dem senators blame Trump for Iran crisis as GOP urges him to stand firm with Israel

The White House has said that any deal with Iran would have to include a full commitment to not developing nuclear weapons, including no uranium enrichment, a necessary step to developing nuclear weapons. Iran has said it will not accept an agreement with a zero enrichment provision. 

"The way to keep Iran from having a nuclear weapon is through negotiation," she said. "We actually had that deal, and Donald Trump threw it out the window."

"That means we lost our inspectors, we lost the plans that had been made," she continued.

"Right now, we need more deconfliction in the area. We need to bring down the temperature between Israel and Iran. That's what's best for Israel and Iran, it's what's best for the region and for the whole world," said Warren.

Sen. Tammy Duckworth, D-Ill., also blamed Trump, saying, "He's the one who put us out the deal in the first place," which she said "very much so" contributed to the ongoing conflict.

While he said the U.S. should not be involved in bombing missions or any other military action against Iran, Sen. Tim Kaine, D-Va., said, "What we should do is continue to provide Israel with all the tools they need to defend themselves."

"I hope the president will continue to promote a diplomatic solution that we had until he tore it up," said Kaine.

Meanwhile, Sen. Angus King, I-Maine, who caucuses with the Democrats, told Fox News Digital that the "question is can it be resolved without our involvement." He said he hopes Iran "will see the light and decide they don't need to keep developing nuclear fuel."

"Israel is being incredibly effective with their military strike against Iran. They've taken out the senior military leadership, the leaders who would wage a war have been one after the other after the other surgically taken out by Israel. They are also taking out missile launch sites, and they're taking out nuclear research sites, the sites where Iran is working to develop a nuclear weapon," Cruz explained.

"Deterrence is always the key," said Sen. Markwayne Mullin, R-Ohio. "This president has been very clear he's all about peace, and he doesn't want to use the might of the United States unless we absolutely have to. I believe deterrence is the best foreign policy, because it shows peace through strength."

That being said, Mullin said Trump has he's been "very clear for over a decade: In no way are we going to allow the Iranian regime, who is the number one sponsor of terror around the world, to have a nuclear weapon."

"So, we need to be prepared to back up Israel if they're not able to do the job, then we need to be able to finish it," he said.